Adaptive patient recruitment in action
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Learn more about how digital patient recruitment can deliver on time when traditional enrollment methods fail.
Strategic agility drives enrollment success
The study demonstrates how proactive and flexible recruitment strategies can achieve enrollment goals under tight, manufacturing-driven timelines. In a chronic fecal incontinence gene therapy trial, the team faced fixed operational deadlines and a limited recruitment window. Through adaptive planning, real-time decision-making, and rapid execution, 1nHealth delivered both the speed required for manufacturing schedules and the quality essential for trial integrity.
A hard manufacturing cutoff created significant time pressure to complete enrollment. Early validation showed that traditional methods would not meet the pace, prompting 1nHealth to develop a rapid-response strategy. A pilot campaign launched immediately, with scalable infrastructure ready to expand within months.
Throughout the process, transparent communication and close sponsor collaboration enabled fast alignment on unconventional, data-driven tactics that ultimately transformed a constrained timeline into a successful recruitment outcome.
Our standard enrollment approach
Under normal conditions, we emphasize precision and validation at every stage.
We begin with feasibility modeling to ensure accurate recruitment timelines, followed by pre-tested messaging where creative is A/B tested prior to launch.
Sites are activated sequentially, with data verified through EDC reconciliation after each visit. Once performance is validated, recruitment scales strategically, ensuring consistency and quality across all sites.
An accelerated enrollment strategy
When faced with compressed timelines, we applied an agile, parallel workflow. Recruitment began immediately through a pilot launch while the broader campaign was still in development.
Creative was optimized live through real-time A/B testing, and sites were engaged early to ensure rapid activation readiness.
Data was jointly reviewed with the sponsor through EDC to maintain quality oversight, and as results confirmed success, the campaign scaled without pause, maintaining both speed and precision.
Patient recruitment excellence through collaboration and data intelligence
In a recent gastrointestinal study, 1nHealth supplemented site-based recruitment to accelerate enrollment. Within five months, digital referrals achieved a 23.6% screen fail rate, compared to 26.9% for site-sourced patients. In fact, referral quality was so high that 1 out of 8 patients who passed our phone screening were randomized.
The final result? We sourced 31% of all randomizations, contributing to the success of the trial and exceeding original sponsor expectations.
View Now: Adaptive Patient Recruitment In Action
Learn more about how digital patient recruitment can deliver on time when traditional enrollment methods fail.
